PRECIOUS

Institutions
  • FB Biologie
Publications
    Herrmann, Valerie L.; Wieland, Daniel E.; Legler, Daniel F.; Wittmann, Valentin; Groettrup, Marcus(2016): The STEAP1262-270 peptide encapsulated into PLGA microspheres elicits strong cytotoxic T cell immunity in HLA-A*0201 transgenic mice : A new approach to immunotherapy against prostate carcinoma The Prostate ; 76 (2016), 5. - S. 456-468. - ISSN 0270-4137. - eISSN 1097-0045

The STEAP1<sub>262-270</sub> peptide encapsulated into PLGA microspheres elicits strong cytotoxic T cell immunity in HLA-A*0201 transgenic mice : A new approach to immunotherapy against prostate carcinoma

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PLGA microsphere-based vaccination has been proven to be effective in immunotherapy of syngeneic model tumors in mice. The critical step for the translation to humans is the identification of immunogenic tumor antigens and potent vaccine formulations to overcome immune tolerance.

Origin (projects)

Funding sources
NameProject no.DescriptionPeriod
Europäische Union507/16no information
Further information
Period: 01.05.2016 – 30.04.2021