Dynamic force field mapping of living cells in a macro-scale transducer array based on flexible semiconductor nanopillars

Description

The project "Dynamic force field mapping of living cells in a macro-scale transducer array based on flexible semiconductor nanopillars" is a collaborative project between Prof. Dr. Eva Weig (University of Konstanz) and Prof. Dr. Doris Heinrich (University of Leiden / Fraunhofer ISC) that is funded by the program Integration of Molecular Components in Functional Macroscopic Systems by the VolkswagenFoundation.The project aims at force field mapping of living cells with a macro-scale transducer. A major goal in biosciences is the detailed understanding of cytoskeleton regulation in living cells. Actin-based force generation and cell motility is central to immune response, cancer metastasis or tissue healing and thus of basic interest for development of advanced biochemical and pharmaceutical cell assays. In this project, we propose flexible micro structures as sensitive force transducer for living cells.

Institutions
  • Department of Physics
Funding sources
Name Finanzierungstyp Kategorie Project no.
Volkswagen-Stiftung third-party funds research funding program 421/15
Further information
Period: 01.03.2015 – 28.02.2017